John Maguire, also known as Abu Anwar Al-Canadi, died on Wednesday.

Five Canadians have died fighting alongside ISIS militants in Syria, including a man who called for lone wolf attacks in Canada, local media reported Wednesday.

The National Post said Ottawa-born John Maguire, who joined ISIS jihadists in Syria in January 2013, died Wednesday in the flashpoint town Kobane.

In a video message last year, the former University of Ottawa student warned Canada it faces retaliation for participating in U.S.-led airstrikes against ISIS.

Calling himself Abu Anwar al-Canadi, Maguire urged Muslims to follow the example of a driver in a hit-and-run killing of a soldier near Montreal and of a gunman who killed an unarmed soldier in Ottawa.

Meanwhile, broadcaster CBC said that four other Canadians from a single family of Somali origin died in recent months while fighting with ISIS in Syria.

Three of the cousins are thought to have left Canada in October 2013, the CBC reported.

Ahmed Hirsi said his 20-year-old son Mahad was killed last fall along with cousins Hamsa and Hersi Kariye.

The CBC said another cousin from Minnesota, Hanad Abdullahi Mohallim, was also killed.

Hirsi said his son had called him from Egypt to say he was traveling to Syria.

Hamsa and Hersi’s brother confirmed the two men had died, but did not say how or where. He denied they had traveled to Syria and said instead they went to Egypt to study Islam.

“That is the path my brothers wanted to take from day one,” he told CBC.

“These people left their country to go study their religion.”

Canada has joined the U.S.-led campaign against ISIS, which has taken over large swathes of territory in Iraq and Syria.

Last week, three were arrested in Canada over “serious” potential threats, Public Safety Minister Steven Blaney said Tuesday.

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