A medic wraps a bandage around an injured girl’s head after what activists said were airstrikes by warplanes loyal to Syria‘s President Bashar al-Assad in Da’el town, north of Daraa, April 19, 2015.

Republican and Democratic U.S. senators called on President Barack Obama on Tuesday to create and enforce humanitarian safe zones in Syria, amid international concerns about the dire conditions faced by millions of people displaced by the war.

“The staggering human displacement, killing and destruction are an affront to the civilized world and must be stopped,” Republican Senators John McCain and Lindsey Graham and Democrats Richard Durbin and Tim Kaine wrote to Obama in a letter seen by Reuters.

The four-year-long war in Syria has killed more than 220,000 people and displaced millions of others.

The lawmakers urged Obama to establish one or more safe zones, with “necessary enforcement mechanisms” including air assets, and securing of the border area by Turkey.

They also asked the Obama administration to provide lawmakers with an update on efforts to alleviate the humanitarian crisis in Syria, including efforts to create and enforce safe zones with U.S. allies.

The senators also said they were disappointed that the United States has not taken in more Syrian refugees during the conflict. The country has admitted fewer than 800.

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