This Oct. 5, 2017 frame grab by Russian Defense Ministry shows a long-range Kalibr cruise missile in the Mediterranean.

:: Russian air strikes killed 14 civilians as they were crossing the Euphrates river near the militant-held town of Mayadeen in eastern Syria, the Syrian Observatory for Human Rights said on Friday.

“They were crossing the river on makeshift rafts in a village south of Mayadeen,” Observatory director Rami Abdel Rahman said, adding that three children were among those killed overnight.

Russia has in recent days intensified its air raids in support of Syrian regime forces battling militants across the country. Abdel Rahman said the civilians were fleeing the village of Mahkan, south of Mayadeen, which lies about 420 kilometers east of Damascus and is one of ISIS’s main remaining bastions.

Mayadeen has been under ISIS control since 2014, when the group swept across swathes of Iraq and Syria but regime forces this week advanced to within five kilometers of the town.